Drug Target Review: Leading Research & Insights in Drug Discovery
Stay at the forefront of drug discovery and therapeutic development with Drug Target Review. Dive into the latest research, industry analysis and technological advancements. Connect with …
Immuno-oncology innovations redefining cancer treatment in 2024
2024年1月23日 · Dr Espen Basmo Ellingsen. University of Oslo . Dr Ellingsen is a Medical Doctor and holds a PhD in cancer immunology from the University of Oslo. Background in …
Tessera Therapeutics: addressing Alpha-1 Antitrypsin Deficiency
2024年6月18日 · Mike Holmes, PhD, Chief Scientific Officer at Tessera Therapeutics. Michael joined Tessera in December 2021 as Chief Scientific Officer. Dr Holmes has over 20 years of …
Scientific workflow for hypothesis testing in drug discovery
2025年1月14日 · In part two of the step-by-step scientific workflow for drug discovery series, Dr Raminderpal Singh and Nina Truter describe the functions of the workflow previously outlined …
Establishing Alpha CETSA HT in primary screening - Drug Target …
2020年6月23日 · Using CETSA ® HT for compound screening and hit confirmation; Applying CETSA ® HT on targets that are lacking chemical starting points; Overcoming challenges …
Bispecific antibodies: the next generation of immuno-oncology …
2020年9月10日 · Figure 1: The dual targeting of CLDN18.2 and 4-1BB by a single bispecific antibody facilitates the bridging of tumour cells and T cells.Only T cells that come into contact …
Drug side effects: an open source tool to predict adverse reactions
2020年7月14日 · A multi-institutional group of researchers led by Harvard Medical School (HMS), US, and the Novartis Institutes for BioMedical Research (NIBR) has created an open-source …
Drug candidates with blockbuster potential for CNS diseases
2024年9月19日 · Based on the positive efficacy and safety data generated in Phase I and II, the plan is to initiate a Phase III programme for mesdopetam. Following successful interactions at …
Exploring alternatives to animal testing in drug discovery
2023年7月6日 · History behind animal testing. In December 2022, the US Government approved the ground-breaking US Food and Drug Association (FDA) Modernization Act 2.0, allowing …
Drug intended to treat Alzheimer’s may hold promise for …
2021年11月24日 · A new study from the Cleveland Clinic, US, has found that found that drugs originally designed to help treat Alzheimer’s disease may hold promise for glioblastoma, the …