Malignant obstruction of the bile duct from cholangiocarcinoma, pancreatic adenocarcinoma, or other tumors is a common problem which may cause debilitating symptoms and increase the risk of subsequent surgery.

Malignant biliary obstruction usually presents with painless jaundice, pruritus, and much less commonly signs and symptoms of infectious cholangitis such as fever and leukocytosis. Other features include dark urine resulting from increased bilirubin content, loss of weight and appetite, nausea, and vomiting.

Malignant biliary obstruction is a challenging condition, requiring a multimodal approach for both diagnosis and treatment. Pancreatic adenocarcinoma and cholangiocarcinoma are the leading causes of malignant distal biliary obstruction.

2016年6月15日 · Malignant obstruction of the bile duct from cholangiocarcinoma, pancreatic adenocarcinoma, or other tumors is a common problem which may cause debilitating symptoms and increase the risk of subsequent surgery. The optimal treatment - including the decision whether to treat prior to resection - depen …

Malignant biliary tract obstruction is a common clinical entity. Patients with tumors causing biliary tract obstruction are often asymptomatic until disease is significantly advanced. Symptoms of obstructive jaundice can significantly impair quality-of-life un-less intervention to decompress the biliary tract, either curative

The diagnosis of malignant biliary obstruction combines the use of clinical evaluation, diagnostic imaging, tissue sampling, and minimally invasive options with the initial goal of identifying candidates for curative resection. The most common causes of obstruction are pancreatic adenocarcinoma and …

This article reviews the evaluation and management of patients with malignant biliary tract obstruction, including the available imaging and treatment modalities (endoscopic, percutaneous, and surgical approach) for relieving malignant biliary tract obstruction.

EUS- versus ERCP-guided biliary drainage for malignant biliary obstruction: a systematic review and meta-analysis of randomized controlled trials.

2024年12月26日 · Comparison of surgical bypass, ERCP, PTBD, and EUS-BD approaches for the management of malignant biliary obstruction.

2016年2月11日 · The most common causes of malignant biliary obstruction (MBO) are pancreatic adenocarcinoma, cholangiocarcinoma, ampullary/duodenal adenocarcinoma, gallbladder adenocarcinoma, lymphoma, and compressive metastatic proximal lymph nodes [9, 10].