2020年9月3日 · Background endometrium with extensive atypical hyperplasia / endometrioid intraepithelial neoplasia Uterus and cervix, hysterectomy: Endometrial endometrioid adenocarcinoma, FIGO grade 1, with deep myometrial invasion (> 50%), focal lymphovascular invasion and extension to lower uterine segment (see synoptic report and comment)

2017年7月1日 · Evolves through endometrial intraepithelial neoplasia (EIN) / atypical hyperplasia to adenocarcinoma (FIGO grade 1) Type 2 (variant types): Most occur "de novo" with no identifiable precursor lesion Serous intraepithelial carcinoma is the proposed preinvasive precursor lesion of endometrial serous carcinoma

2023年9月26日 · CIN2+ detected but no glandular neoplasia Manage per 2019 ASCCP guidelines Atypical glandular cells, favor neoplastic If no adenocarcinoma in situ (AIS) or invasive carcinoma are detected by colposcopy / biopsy, then proceed to diagnostic excisional procedure Atypical endometrial cells Endometrial and endocervical sampling is recommended

2020年1月31日 · Also known as high grade cervical glandular intraepithelial neoplasia (HG-CGIN); please note that this terminology is not recommended by the WHO classification Cytology (IARC: Cytopathology of the Uterine Cervix - Digital Atlas [Accessed 30 January 2020]): Endocervical adenocarcinoma in situ Atypical endocervical cells, favor neoplastic

2023年5月10日 · Two tier grading is preferred: low grade squamous intraepithelial lesion (LSIL) / high grade squamous intraepithelial lesion (HSIL) HSIL may be subdivided into cervical intraepithelial neoplasia II (CIN II) and cervical intraepithelial neoplasia III (CIN III), particularly in young women (significantly higher regression rate in the former)

2022年1月18日 · Changes in squamous cells associated with human papillomavirus (HPV), encompassing clinically actionable lesions previously referred to as moderate dysplasia, severe dysplasia, cervical intraepithelial neoplasia (CIN) 2, CIN 3 and carcinoma in situ (CIS) (Arch Pathol Lab Med 2012;136:1266, J Low Genit Tract Dis 2013;17:S1, Nayar: The Bethesda …

Benign (non-atypical) endometrial hyperplasia Atypical endometrial hyperplasia / endometrioid intraepithelial neoplasia The terms “simple” and “complex” have been removed from the classifi-cation, as they are not reproducible or significantly associated with differences in malignant outcome. The term “endometrial intraepi-

2023年5月3日 · Negative for intraepithelial lesion or malignancy Epithelial cell abnormality: specify squamous or glandular (see Interpretation / result) Other (e.g., endometrial cells in a woman ≥ 45 years of age) (see Interpretation / result) (Nayar: The Bethesda System for Reporting Cervical Cytology, 3rd Edition, 2015)

• HPV-associated squamous intraepithelial lesions (formerly known as vulvar intraepithe-lial neoplasia of the usual / classic type) repre-sent the majority (90%) of precursors. They are referred to as low-grade (LSIL, equivalent to uVIN1) and high-grade (HSIL, equivalent to uVIN2 and uVIN3). - HSIL is characterized by p16 overexpression

2024年12月17日 · After ruling out significant endometrial pathology that can lead to abnormal uterine bleeding (e.g., endometrial polyp, hyperplasia, atypical hyperplasia, carcinoma, leiomyoma [submucosal], endometrial stromal tumors, endometritis, exogenous hormone effects, pregnancy related bleeding), a simplified descriptive sign out of these cases is ...