Background Recent research has shown that behavioural symptoms in Huntington’s disease (HD) have a significant impact on patients’ quality of life and function. Accurate assessment of behavioural ...

Objectives: To test a new neurological sign, the “abductor sign,” which can distinguish between organic and non-organic leg paresis using synergic movements of the bilateral hip abductors. Methods: ...

OBJECTIVES Increased resistance to stretch of muscles after stroke may be the result of centrally mediated neural factors such as spasticity or local, peripheral factors such as muscle contracture or ...

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3 Working Group ‘Deep Brain Stimulation in Psychiatry: Guidance for Responsible Research and Application’. This Working Group is organised by the Europäische ...

The past few decades have seen growing interest in the neuropsychiatric syndrome of apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed behaviour. Apathy occurs ...

Objective Deep brain stimulation (DBS) reduces depressive symptoms in approximately 40%–60% of patients with treatment-resistant depression (TRD), but data on long-term efficacy and safety are scarce.

Background To delineate the clinical characteristics and outcomes of late-onset myelin oligodendrocyte glycoprotein antibody-associated disease (LO-MOGAD) and compare them with those of early-onset ...

Dr JL Iddon, Department of Academic Neurosurgery, Box 167, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 5RG, UK email jo.iddon{at}cenes.co.uk OBJECTIVES Eleven patients ...

a Department of Clinical Neurosciences, b Department of Neuroimaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, Saisho-ko, Himeji, Japan Dr Nobutsugu Hirono, Department of ...

Background Dysfunction of the locus coeruleus-noradrenergic system occurs early in Alzheimer’s disease, contributing to cognitive and neuropsychiatric symptoms in some patients. This system offers a ...

Objective Depression and trauma are associated with changes in brain regions implicated in Alzheimer’s disease. The present study examined associations between childhood trauma, depression, adult ...