Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, ...

Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.

A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

Why do authors choose the eLife Model? We spoke to Hironori Funabiki at the Rockefeller University to learn his reasons.

As Editor-in-Chief, Behrens is responsible for the editorial direction and vision of the journal, providing leadership to ...

Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Global biodiversity is declining at an unprecedented rate, with agriculture as a major driver. There is mounting evidence that intercropping can increase insect biodiversity while maintaining or ...

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Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...