In principle, mRNA vaccines are ideal for health emergencies as they can be quickly mass produced using a template. The problem is that current cell-based template production methods take too long, ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Utrophin increase in muscle cells after transcriptional adaptation normalises cell function in Duchenne muscular ...

AIM Vaccine Co., Ltd. (06660.HK), a leading PRC vaccine company, published an announcement on February 11, 2025, announced that its independently developed mRNA shingles vaccine has been submitted for ...

Duchenne muscular dystrophy (DMD) is a rare hereditary disease that is associated with progressive muscle wasting. The ...

New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), ...

Researchers have produced a review of chromatography media and purification processes for handling complex and super-large ...

In eukaryotes, the process of mRNA decay generally involves loss of the 3′ poly(A) tail and removal of the cap by a decapping enzyme (Dcp2). The body of the mRNA is then degraded from the 5 ...

On Monday, a federal judge temporarily averted disaster by halting the Trump administration’s plans to slash federal funding ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...