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生物通
1 个月
己糖激酶i直接与线粒体VDAC1和VDAC2的带电膜埋谷氨酸结合
一、研究背景 电压依赖性阴离子通道(VDACs)是线粒体 outer membrane(OMM)上丰富的 β - 桶状蛋白,在离子、代谢物转运以及细胞凋亡调控等过程中发挥核心作用。在哺乳动物中,VDAC1 和 VDAC2 是大多数组织中表达最丰富的同工型,除了控制代谢物跨 OMM 的流动外 ...
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