(Ursodiol [Urso] is a prescription medication that’s also known as ursodeoxycholic acid ... as metabolism and production of bile acid. By Ocaliva’s mechanism of action, FXR reduces how ...

Now, in a stunning reversal, Advanz has won a reprieve after the General Court of the European Union ordered a suspension of the EC's decision, meaning the license for Ocaliva (obeticholic acid ...

That leaves patients with limited second-line options for treatment if they fail to respond to or cannot tolerate ursodeoxycholic acid (UDCA ... [it] has a different mechanism of action from ...

Bile reflux gastritis (BRG) is a gastro-intestinal condition especially characterized by the reflux of bile into the stomach, further leading to mucosal inflammation along with various other clinical ...

The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis, for instance by involving a combination of several different types of catalysis. Determining enzyme ...

Lissencephaly is a severe neurodevelopmental disease often caused by mutations in the Dcx gene. Using a human cellular model of lissencephaly, the authors report that DCX restricts neuronal ...