Tau protein and beta-amyloid, key factors in Alzheimer's disease, impact brain circuits differently, with tau affecting memory-related areas and beta-amyloid influencing emotional centers.
pathology is found in a considerable portion of patients with Parkinson's disease (PD), particularly those with early dementia (PDD). Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau ...
Tau is an amazing protein that plays a key role in cognitive processes ... cortical basal degeneration, dementia pugilistica, Pick’s disease, progressive supranuclear palsy, tangle-only dementia, ...
this protein has been found to contribute to some neurodegenerative diseases, broadly defined as tauopathies. Specifically, past research linked the levels of tau in the brains of patients ...
Traumatic brain injury (TBI), Alzheimer’s disease (AD), and epilepsy share proposed mechanisms of injury, including neuronal excitotoxicity, cascade signaling, and activation of protein biomarkers ...
Researchers from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) have found that tau protein and beta-amyloid – two pathological hallmarks of Alzheimer’s disease – ...
One of the key features of Alzheimer’s disease is an accumulation of a harmful protein called tau. In a healthy brain, tau primarily helps to support and stabilise brain cells (neurons).
The Swiss pharma group is paying $120 million upfront for exclusive global rights to UCB0107, an anti-tau antibody that is in a phase 1 trial in another disease ... Tau is a protein that ...