Tau protein and beta-amyloid, key factors in Alzheimer's disease, impact brain circuits differently, with tau affecting memory-related areas and beta-amyloid influencing emotional centers.

pathology is found in a considerable portion of patients with Parkinson's disease (PD), particularly those with early dementia (PDD). Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau ...

Traumatic brain injury (TBI), Alzheimer’s disease (AD), and epilepsy share proposed mechanisms of injury, including neuronal excitotoxicity, cascade signaling, and activation of protein biomarkers ...

Researchers from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) have found that tau protein and beta-amyloid – two pathological hallmarks of Alzheimer’s disease – ...

The Swiss pharma group is paying $120 million upfront for exclusive global rights to UCB0107, an anti-tau antibody that is in a phase 1 trial in another disease ... Tau is a protein that ...

OBJECTIVES The detection of the protein 14–3–3 in the CSF has been shown to be a reliable and sensitive marker for sporadic Creutzfeldt-Jakob disease (CJD). Other brain-specific proteins such as ...

TauRx Pharma's effort to bring a tau-targeting drug for Alzheimer's disease (AD ... see a 5-point decline over that period. Tau is a protein that is found in cells of the central nervous system ...

6, 2025 — A research team has discovered that the two key pathological hallmarks of Alzheimer's -- tau protein and beta ... Depression and Alzheimer's Disease Feb. 5, 2025 — New research ...

Apr. 1, 2021 — Researchers have uncovered a long-sought link in the battle to control cholesterol and heart disease. The protein that interferes with low-density lipoprotein (LDL) receptors that ...

No significant difference in plasma biomarkers was found among patients with different disease severity. This study aimed to evaluate the ability of plasma biomarkers, including Aβ, t-tau, and NfL, to ...

Specifically, CBD and PSP tend to spare the temporal lobes, whereas SD involves basal ganglia only late in the disease, and SD is usually associated with ubiquitin, not tau, inclusions.