Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

Even though human behavior and emotions fall within a defined range of expressions, one puzzle remains: why aren’t these ...

First ever head-to-head comparison of gut microbiome changes associated with ibezapolstat (IBZ) to other anti-CDI antibiotics in a germ-free mouse ...

Hepatic biliary adenofibroma (BAF) is a rare benign bile duct neoplasm that has garnered increasing attention due to its potential role as a precursor lesion for intrahepatic cholangiocarcinoma ...

Hepatology is a medical specialty focusing on the structure, function, pathology and disorders of the liver, gall bladder and bile ducts. Metabolic dysfunction-associated steatotic liver disease ...

Conclusion: HSD caused dysbiosis of the intestinal microbiota such as increased Lactobacillus, along with enhanced BSH activity and excessive unabsorbed free bile acids. This resulted in ileal ...

A diet rich in produce such as grapes, strawberries, açaí, oranges, chocolate, wine and coffee can reduce the risk of metabolic syndrome by as much as 23%, according to the findings of a study ...

Yellow or greenish-vomit is usually a sign that you are throwing up bile. Bile is a digestive fluid produced by the liver. Throwing up yellow bile could indicate a potentially serious medical concern ...

What are bile ducts? The bile ducts are small, tubular structures that play an important role in digestion by transporting bile -- a yellowish-green fluid -- from the liver and gallbladder to the ...

Every year, 10 million people contract tuberculosis (TB), a disease caused by the bacterium Mycobacterium tuberculosis (Mtb), and approximately 1.5 million patients succumb to the disease.

Once produced by the liver, bile is secreted through tiny canals into a structure called the common bile duct. From there, bile is fed to the gallbladder, where it is stored and released on demand ...

Introduction: Cholangiocarcinoma (CCA) is a malignant tumor of the biliary epithelium with a poor prognosis. The lack of biomarkers to predict therapeutic response and prognosis is one of the major ...