The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...
Here, the authors introduce NetFlow3D, a framework for integrating protein structure and interaction networks to map the mechanistic effects of somatic mutations in cancer.
University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage.