The U.S. Food and Drug Administration (FDA) approved suzetrigine under the brand name Journavx on Jan. 30, 2025. Journavx is a first-in-class non-opioid painkiller that acts on sodium channels in ...

Isotretinoin is indicated for nodular acne or severe acne that is unresponsive to conventional therapies. The usual dose is 0.5 to 1.0 mg/kg/day for 20 weeks, or a cumulative dose of 120 mg/kg.

Patients with cirrhosis due to MASH have a severe form of the disease with few treatment options outside of a liver transplant. Once MASH progresses to cirrhosis, median survival is about five ...

which is defined as acne affecting those over 25, is much more persistent. "It often manifests as cystic breakouts, painful nodules or pustules, especially around the jawline, chin and lower face. It ...

After more than a decade of dealing with adult acne, Bazaar's beauty editor shares the skincare routine she uses to help manage blemishes – with advice from skin experts and dermatologists ...

She started the thread by writing, "I have Tourette Syndrome. As a teenager, my doctor said it was the most severe case she’d ever seen. AMA [Ask Me Anything]. I was diagnosed in my teens (I’m ...

Sophie Pierce will be the first person with cystic fibrosis to do just that, travelling from Lanzarote to Antigua. A historic achievement when you consider what she's been through and when ...

Doctors report severe flu symptoms lasting longer than usual, with some cases leading to pneumonia or secondary infections. Handwashing and flu shots remain essential defenses, though this year ...

People with severe mental illness are more likely to die prematurely in Manchester than anywhere else in the country. For every 100,000 people with severe mental illness, there were 233 deaths in ...

Cystic acne is a severe form of acne that goes beyond typical breakouts, causing deep, painful cysts under the skin. If left untreated, it can cause scarring and emotional distress. Cystic acne can ...

Figure 4. Inflamed papules and pustules, features of severe acne vulgaris. Figure 5. Nodular and cystic lesions may appear in extreme cases of acne, causing severe scarring. Aggravating factors in ...