Incidence peaks in individuals over 70 years of age (3.06/100,000). 6 The Carney triad, caused by mutation of the SDH gene, is a rare, nonhereditary condition characterized by the presence of 3 ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

Mechanisms of the spread of Krukenberg tumor proposed are retrograde lymphatic dissemination involved in gastric cancer metastases, hematogenous spread most frequent in colorectal cancer, and ...

A brain tumor is a mass of abnormal cells that grow in the brain. Brain tumors can be benign (non-cancerous) or malignant (cancerous) and can start anywhere in the brain. Malignant tumors grow rapidly ...

Characterizing the tumor immune microenvironment enables the identification of new prognostic and predictive biomarkers, the development of novel therapeutic targets and strategies, and the ...

Regarding the effect of biliary disease on colitis, there are some open questions following the presented experiments. The study by Bedtke et al does not answer whether it is sclerosing cholangitis ...

A tumor can metastasize within its organ of origin or in other organs, potentially causing pressure, obstruction, and dysfunction. Metastases are associated with a lower cancer survival rate. What is ...

H. Ma and S. Srivastava are joint first authors of this article. R. Sundar and P. Tan are joint corresponding and senior authors of this article.

Targeting cytotoxic T lymphocytes (CTLs), as chimeric antigen T cells (CAR-T), T cell receptor-engineered (TCR)-T cells or adoptive cell transfer of tumor infiltrating T cells (TILs) to solid tumors ...

Table 1 Antibody-mediated and genetic depletion models for the in vivo study of basophils in different pathological conditions. The authors also evaluated the cytokines produced in the heart 3 days ...