Ribonucleic acid ... The new RNA sequences are complementary to their DNA template, rather than being identical copies of the template. RNA is then translated into proteins by structures called ...

The structure and chemistry of nucleic acids is fundamental to their function, from the DNA double helix discovered by Watson and Crick to the intricate secondary and tertiary structures adopted by ...

Nucleic acids are complex biological molecules that store and transmit genetic information ... In DNA, two complementary strands of nucleotides pair up through hydrogen bonds between the bases (A with ...

Along with DNA, the other major type of nucleic acid in cells is ribonucleic acid (RNA). Both are shown in the above image, in single stranded form. DNA at on the top, and differs from RNA by its ...

The properties of nucleic acids to adopt secondary structures such as hairpins, triplexes, quadruplexes, and i-motifs, etc., can control basic cellular processes, and thus altered levels of gene ...

An example of inhibitory RNA aptamers binding the NF-kappaB transcription factor by molecular mimicry of the normal DNA target from the Nucleic Acid Structure and Recognition Lab led by Dr. Maher at ...

Source code is available for GNU/Linux distributions. QRNAS is a software tool for fine-grained refinement of nucleic acid structures, dedicated to improving the quality of models generated by low- to ...

It is increasingly clear that small RNA molecules play roles in natural gene regulation. Can new examples be engineered? The Nucleic Acid Structure and Recognition Laboratory seeks to use RNA as the ...

A variety of chemical modifications decorate the nucleic acids, increasing the alphabet of DNA to about a dozen known nucleotide variants. The alphabet of RNA is even more impressive, consisting of at ...

Much of our work relies on peptide nucleic acid (PNA. Figure 1), a DNA mimic invented at the University ... to hybridize to a complementary DNA target embedded within a folded G-quadruplex structure. ...

48. Arteaga, S. J., Dolenz, B. J., and Znosko, B. M. (2024) "Competitive influence of alkali metals in the ion atmosphere on nucleic acid duplex stability," ACS Omega ...

In plants, secondary and tertiary RNA structures, such as G-quadruplexes ... The model also identified conserved Kozak sequence motifs — nucleic acid motifs that initiate protein translation ...