生命科学Life science2025年2月7日，中山大学王金凯团队在Cell Press细胞出版社旗下期刊Molecular Cell在线发表题为“Single-molecule m6A detection empowered by ...
News Medical on MSN3d
Study identifies vitamin E succinate as key to tumor growth controlHigh levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...
A new study published in Advanced Science has revealed how curcumin, a bioactive compound found in Curcuma aromatica (Yujin), ...
直接RNA测序（DRS）技术 ... CXCL10 mRNA的稳定性通过YTHDF1介导的m6A位点识别维持。 pum6a不仅扩展了m 6 Anet的功能，还通过整合电信号和碱基配对特征 ...
N 6-甲基腺苷 (m 6 A)是目前在不同物种中研究最为广泛的RNA修饰，m 6 A修饰在免疫系统中的重要作用已经被充分揭示，包括了mRNA代谢、细胞分化、增殖 ...
More information: Yoshiki Ochiai et al, SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency, Nucleic Acids Research (2024). DOI: 10.1093/nar/gkae887 ...
Vitamin E succinate has been found to inhibit tumor growth and enhance the effectiveness of immunotherapy by targeting ...
近日，美国得克萨斯大学西南医学中心Yunsun Nam团队揭示了癌症相关突变如何通过改变METTL3-METTL14复合体对RNA甲基化（m6A）的特异性来促进肿瘤发生。研究发现，METTL14的R298P突变能够改变m6A的序列偏好，优先修饰含有GGAU ...
N6-甲基腺嘌呤（N6-methyladenosine，m 6 A）作为最常见的一种转录后修饰，在真核生物中高度保守，介导了超过半数的RNA甲基化。m6A修饰普遍存在于mRNA 和多种类型的非编码RNA，通过影响RNA加工成熟 ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback