生命科学Life science2025年2月7日，中山大学王金凯团队在Cell Press细胞出版社旗下期刊Molecular Cell在线发表题为“Single-molecule m6A detection empowered by ...

近日，美国得克萨斯大学西南医学中心Yunsun Nam团队揭示了癌症相关突变如何通过改变METTL3-METTL14复合体对RNA甲基化（m6A）的特异性来促进肿瘤发生。研究发现，METTL14的R298P突变能够改变m6A的序列偏好，优先修饰含有GGAU ...

癫痫是一种严重的神经系统疾病，反复发作不仅会导致神经元损伤，还会广泛激活脑内胶质细胞，引发局部免疫应答，释放促炎因子，从而加重病情，形成恶性循环。中医药自古以来便采用“白金丸”治疗癫痫，其中，郁金的主要药效活性成分姜黄素近年来被发现可能通过调节中枢神 ...

A new study published in Advanced Science has revealed how curcumin, a bioactive compound found in Curcuma aromatica (Yujin), ...

Vitamin E succinate has been found to inhibit tumor growth and enhance the effectiveness of immunotherapy by targeting ...

United States Center for RNA Technologies and Therapeutics, University of California San Diego, La Jolla, California 92037, United States Chemical Genomics Centre, Max Planck Institute of Molecular ...

Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, United States Department of Biochemistry and Structural Biology, University of ...

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...

【导读】目前，靶向晚期透明细胞肾细胞癌（ccRCC）的治疗选择尚不充分。早期研究已表明，甲基转移酶样蛋白 14（METTL14）可通过 N6-甲基腺苷（m6A）的修饰来抑制 ccRCC ...

RNA (ribonucleic acid) is a nucleic acid polymer where the carbohydrate is ribose. RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is ...