SLC25A1 drives citrate export from the mitochondria to the cytosol, where it fuels acetyl-CoA synthesis by ATP citrate lyase (ACLY). This acetyl-CoA supply sustains FSP1 acetylation and prevents its ...

MANILA, Philippines — The Commission on Audit (COA) has called out the Philippine Atmospheric, Geophysical and Astronomical Services Administration (PAGASA) over P256.07 million worth of ...

Here, we examined the effect of different carbon sources that are involved in the major metabolic pathways of acetyl-CoA synthesis on myocardial infarction and found that elevation of acetyl-CoA by ...

This manuscript is of particular interest to the community of fungal biologists, along with a broader audience studying epigenetic and protein post-translational modifications. The authors combine ...

Overnight liquid pre-cultures were diluted 1:100 into fresh media (500 ml), and growth was continued at 37°C with agitation ... The effect of inclusion of the TfAcCCE subunit on the carboxylation of ...

Here, we demonstrate that pyruvate dehydrogenase kinase (PDK), which inhibits the pyruvate dehydrogenase-mediated conversion of cytosolic pyruvate to mitochondrial acetyl-CoA, functions as a metabolic ...