The chemistry of amino acid side chains is critical to protein structure because these side chains can bond with one another to hold a length of protein in a certain shape or conformation.
While AlphaFold and the subsequent AI revolution in biology garnered a lot of attention, the foundational bricks for the strides made in protein structure and design today were laid over the ...
David Baker, Demis Hassabis, and John Jumper share this year’s Chemistry award for their research on protein design and structure prediction. Sneha Khedkar is an Assistant Editor at The Scientist. She ...
MS, an experimental protocol combining high-resolution protein fractionation using SDS-polyacrylamide gel electrophoresis (SDS-PAGE) with the latest mass spectrometry technology to enable highly ...