In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

There are 210 thousand experimentally determined protein structures but 250 million known protein sequences. Initiatives like the EarthBioGenome project could generate billions more protein ...

Proteins, the essential molecular machinery of life, play a central role in numerous biological processes. Decoding their intricate sequence, structure, and function (SSF) is a fundamental pursuit in ...

Introduction: Recent advances in 3D structure-based deep learning approaches demonstrate improved accuracy in predicting protein-ligand binding affinity in drug discovery ... We demonstrate our method ...

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...

"I see in 3D" (iCn3D) Structure Viewer is not only a web-based 3D viewer, but also a structure analysis tool interactively or in the batch mode using NodeJS scripts based on the npm package icn3d.

In addition, considering the complexity of this area, more research is needed to explore the exact processes and factors of changes in water mass structure. Biomarkers for marine algae and terrestrial ...

If the user is familiar with nginx or apache, VRPG can be further configured using any of them. For graphs generated by PGGB, the duplicate sequence in the primary linear reference assembly might have ...

Identity (%): sequence identity thresholds. Coverage (%): Alignment coverage of the leader sequence. Compression (%): percentage of the original size. Affected clusters: number of clusters with ...