Proteins, the essential molecular machinery of life, play a central role in numerous biological processes. Decoding their intricate sequence, structure, and function (SSF) is a fundamental pursuit in ...

This database not only provides essential information about protein sequences but also incorporates structures predicted by AlphaFold, enhancing the understanding of protein functions and ...

There are 210 thousand experimentally determined protein structures but 250 million known protein sequences. Initiatives like the EarthBioGenome project could generate billions more protein ...

A linear sequence repeatedly increases or decreases by the same amount. The number added (or subtracted) at each stage of the linear sequence remains the same. STEP 1 - You can solve problems ...

To determine the three-dimensional structure of small proteins such as transthyretin, researchers often turn to crystallography, in which proteins are forced into a large, repetitive crystal ...

Experiments demonstrate that our TaxDiff achieves state-of-the-art results in both taxonomic-guided controllable and unconditional protein sequence generation, excelling in structural modeling scores ...

opening up unprecedented possibilities in protein engineering. Illustration image Pixabay ESM3 stands out for its ability to integrate sequence, structure, and function of proteins, offering a novel ...

The core S4 model is a linear sequence ... the primary way for training is through the convolution view, which proceeds in two steps. The S4 kernel can then be used in any vanilla CNN block. It is ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

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School of Chemistry, University of Bristol, Cantock’s Close, Bristol BS8 1TS, U.K. School of Chemistry, University of Bristol, Cantock’s Close, Bristol BS8 1TS, U ...