The availability of large-scale protein-protein interaction data has led to the recent popularity of the study of protein interaction networks. Just as the enormous amount of available sequence ...

The identification of protein interactions has been greatly simplified by the invention of yeast-based screening assays such as the yeast two-hybrid system. However, yeast two-hybrid assays cannot ...

enabling scientists to engineer novel protein-protein interactions that play key roles in cell regulation and therapeutics. A year and a half later, the team has reported -- again in Nature-- an ...

A novel geometric deep learning framework designs ligand-specific protein binders, enhancing therapeutic potential in cell therapies and synthetic biology.

Vimentin is a type III intermediate filament (IF) protein normally expressed in cells that develop into connective tissue, ...

that revolutionizes the study of protein-protein interactions by simplifying detection while improving measurement accuracy. Interactions between proteins play a significant role in biological ...

Although powerful, microarray chips did not provide any information about the proteins bound to the DNA and how they might affect gene expression. To uncover the sites of protein-DNA interactions at ...

This sequence ultimately dictates the protein's three-dimensional structure and function. Proteins often interact with other proteins to form complexes or networks that carry out specific biological ...

Researchers at Durham University have achieved a major advancement in understanding how proteins bind metals inside cells, a process crucial to life. The study, published in Nature Communications, ...

London, UK – 11 February 2025 – Bind Research was today launched as the UK’s first not-for-profit Focused Research Organisation (FRO), committed to transforming drug discovery by targeting disordered ...