The linear sequence of amino acids within a protein is considered the primary structure of the protein. Proteins are built from a set of only twenty amino acids, each of which has a unique side chain.

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands ...

The central dogma of molecular biology suggests that the primary ... the structure of DNA was first elaborated, scientists have learned that RNA does much more than simply play a role in protein ...

This internal cap structure triggers translation initiation, bypassing the need for IRES sequences, and significantly improves the efficiency of protein synthesis. Abe and his colleagues developed ...

Researchers have now revealed the specific shape and structure of one of the body's most important yet complicated proteins: ApoB100. Acting as a kind of molecular exoskeleton, this protein wraps ...

The sequence of amino acids in a protein, known as its primary structure, determines its unique three-dimensional shape and function ... such as glucose or fatty acids. Disorders of amino acid ...

and other gut-related disorders. This highlights potential therapeutic strategies to restore proteostasis. The endoplasmic reticulum (ER) is the primary site of protein folding and processing.