A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.

As part of the natural exchange, plasmids often provide recipient bacteria with genetic advantages. For example, many antibiotic-resistance genes spread through plasmid transfer between bacteria.

Together, this complex shuts off gene expression to keep the plasmid safe within its bacterial host. This newly discovered mechanism offers a fresh insight into long-range gene silencing in bacteria.

Fu and colleagues used Vibrio cholerae bacteria as a model for studying the plasmid defense system known as DdmDE, consisting of proteins called DdmD and DdmE, using cryo-electron microscopy to ...

1 To explore this question, I transformed mutated EF-hand sequences into bacteria using plasmids to obtain larger plasmid amounts for my protein expression experiments. One day, I was getting ready to ...

researchers revealed that KorB, a DNA-sliding clamp capable of traversing long genomic distances, is captured by KorA to form a stable transcriptional co-repressor complex on a bacterial plasmid.

(5) Scientists edit the microbe’s DNA or cause irreparable breaks that lead to DNA degradation. (6) In bacteria, scientists modify either the plasmid or chromosomal DNA of the microbe. In complex ...

Plasmid DNA, or simply plasmids ... The most common used applications for plasmids within the Biopharmaceutical space are bacterial vector Cloning, Protein Production, Gene Therapy and different ...

Together this complex shuts off gene expression to keep the plasmid safe within its bacterial host. This newly discovered mechanism offers a fresh insight into long-range gene silencing in bacteria.