As expected, OA-StOBs were enriched for genes involved in ECM binding and collagen fibril organisation ... It is known that SB starts to undergo remodelling processes before evident cartilage ...

The term osteoarthritis refers to a group of disorders that result in the primarily mechanically induced structural and functional failure of synovial joints. Here, the authors show that reduced ...

Zhejiang University, Hangzhou, Zhejiang, China; hwoy{at}zju.edu.cn Objectives This study investigated the stage-specific and location-specific deposition and characteristics of minerals in human ...

Data sources: Medline, Embase, Scientific Citation Index, CINAHL, Cochrane Library, and conference abstracts in the past 2 years from the British Society for Rheumatology, the European League Against ...

Mechanical damage is one of the predisposing factors of inflammation, and it runs through the entire inflammatory pathological process. Repeated or persistent damaging mechanical irritation leads to ...

2011b). The bioscaffolds function as interim substitutes for the extracellular matrix (ECM), as they duplicate the advantageous properties of the natural ECM, providing a three-dimensional (3D) ...