A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of ...

NK cell lines as therapy NK-92 is a human NK-cytotoxic cell line that represents a pure allogeneic activated NK cell source. NK-92 is IL-2 dependent, lacks KIRs, and has been shown to be cytotoxic ...

Methods: Here, we assess the efficacy of clinically usable CAR-engineered NK cell line NK-92/5.28.z against ErbB2-positive RMS in vitro and in a metastatic xenograft mouse model. Results: Our results ...

SR-91 is a natural killer (NK)-resistant leukemic cell line expressing a low level of ICAM-1. Pre-treatment of SR-91 cells with TNF-α or IFN-γ, increased both ICAM-1 (CD54) expression on SR-91 ...

It is the first comprehensive cellular analysis of ALS, carried out using single-cell RNA sequencing in 14 patients and 14 ...

NK cells are part of the innate immune system, a first line of defense that doesn't need to be primed into action. The latest collaboration will focus initially on NK therapies for leukaemia and ...

other cytotoxic lymphocyte cell subsets have unique phenotypes and capabilities that might be of additional benefit in AML treatment. Of particular interest are the natural killer (NK) and ...

Medical review of Phase 1 cohorts demonstrated no safety issuesData to be presented at the 10th Annual Innate Killer Summit, March 3-5 BOCA RATON, Fla, Feb. 12, 2025 (GLOBE NEWSWIRE) -- INmune Bio Inc ...

A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of ...

The article by Piersma et al. aims to reduce the complex process of NK cell licensing to the action of a single inhibitory receptor for MHC class I. This is achieved using a mouse strain lacking all ...