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由 Chloe S. Adams、Hyojin Kim 等多位学者合作完成的研究成果 “De novo design of protein minibinder agonists of TLR3” 发表于《Nature Communications》期刊 ... 分析突变对结合亲和力的影响,生成热图。 (五)组合文库制备 从单点饱和突变(SSM)热图中筛选增强亲和力的突变 ...