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TABLE 1. TCGA cancer types analyzed. Protein expression of KIF2C was evaluated using the UALCAN online analysis software (http://ualcan.path.uab.edu/index.html ...

Particularly, we are interested in how the distinct motors myosin, dynein and kinesin coordinate to transfer the endosome smoothly from the actin to the microtubule network, ensuring precise ...

Fiji/ImageJ Cell Counter plugin was used to quantify the total number of microtubules within each axon. Only DRG axons with a diameter between 6-11 µm were quantified. The density of microtubules was ...

Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States Wallace H. Coulter Department of ...

Our laboratory studies kinesin and dynein, the two types of motors that move along microtubule tracks. The mechanism of kinesin is reasonably well understood through measurements of its single ...

Microtubules are cylindrical polymers composed of alpha and beta tubulin. They are a major component of the cytoskeleton and mediate crucial cellular functions including formation of the mitotic ...

This study offers important insights into KIF1A-associated neurological disorder (KAND), a group of neurological disorders connected to KIF1A, a microtubule-based motor protein responsible for axonal ...