Plant cells form acentrosomal spindles with microtubules (MTs) converged toward two structurally undefined poles by employing MT minus end-directed Kinesin-14 motors. To date, it is unclear whether ...

CEO & Founder @ DrOmics Labs | PhD Translational Bioinformatics | Wellness DNA Test| Sports DNA Test | Precision Medicine | Computational Biology Innovations | Promoting Genetic Testing In India ...

indicated with cerulean arrows), peripheral doublet microtubules (DMTs, indicated with orange arrows), inner dynein arms (IDAs, indicated with green arrows) and outer dynein arms (ODAs, indicated with ...

This valuable study reports on the critical role of ANKRD5 (ANKEF1) in sperm motility and male fertility. However, the supporting data remain incomplete. This work will be of interest to biomedical ...

In humans, microtubules are composed of various tubulin isoforms:α-tubulin, β-tubulin, γ-tubulin, δ-, ϵ-, and z- tubulin (33). The heterodimers of α- and β-tubulin are the basic structural components ...

However, a successful therapy has not yet been found, partly because the molecular pathogenesis is largely elusive. Here we show that KIF12 kinesin suppresses MASH development by accelerating the ...

Our laboratory studies kinesin and dynein, the two types of motors that move along microtubule tracks. The mechanism of kinesin is reasonably well understood through measurements of its single ...

Image credit: Andrew Kennard (University of Massachusetts, Amherst). The long tail of a sperm cell, the finger-like cilia in the lungs, and the long axons of nerves are all built with ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

This study offers important insights into KIF1A-associated neurological disorder (KAND), a group of neurological disorders connected to KIF1A, a microtubule-based motor protein responsible for axonal ...