The blood-CSF barrier has been far less studied than the blood-brain barrier. Scientists have detected age-related changes in gene expression in the choroid plexus, and have linked these to increased ...
The four colony-stimulating factors (CSFs) are glycoproteins that regulate the generation and some functions of infection-protective granulocytes and macrophages. Recombinant granulocyte-CSF (G ...
Savara Inc. (Nasdaq: SVRA) (the Company), a clinical stage biopharmaceutical company focused on rare respiratory diseases, ...
The presence of the CSF-1 receptor may identify both macrophages, as well as CSF-1-producing tumor cells. Identification of the CSF-1 receptor by immunohistochemistry in human breast tumors is ...
Y-mAbs Therapeutics (YMAB) announced the publication of interim data from a Phase 2 clinical trial evaluating naxitamab with ...
Spotting an opportunity, Coussens explored if preventing tumors from signaling to macrophages would slow tumor progression. Using pexidartinib, they targeted the CSF-1 receptors on macrophages. CSF-1 ...
The Simple, No-cost Test Can Detect Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Autoantibodies in the Blood with Only a Finger Prick -- Savara Inc. (Nasdaq: SVRA) (the Company), a ...
Y-mAbs Therapeutics, Inc. (the “Company” or “Y-mAbs”) (Nasdaq: YMAB), a commercial-stage biopharmaceutical company focused on the development and commercialization of novel radioimmunotherapy and ...