Moreover, the role of specific amino acids in CYP17A1 has been investigated, particularly Asparagine 202, which appears to influence substrate preference and the efficiency of the lyase reaction.

We aimed to evaluate the role of an ATP-citrate lyase inhibitor as a novel treatment for obesity-related nephropathy ... which were amplified by SYBR Green and the Roche LightCycler 480 system. In a ...

Abiraterone (Zytiga) is an oral, selective and potent irreversible inhibitor of CYP17A, which is an enzyme that catalyzes both 17 alpha-hydroxylase and 17, 20-lyase reactions. It blocks androgen ...

Allergies are an immune system reaction to substances called allergens. The cause a range of symptoms from a stuffy nose to itchy eyes to difficulty breathing. How long allergies last varies based on ...

Department of Cell & Molecular Biology, Uppsala University, Biomedical Center, SE-751 24 Uppsala, Sweden ...

Previous experimental studies have suggested that the force applied by the ball to the system accelerates the chemical reaction, but it is not well understood how macroscopic forces influence ...

Sarah Vine and Andrew Pierce bring their own no-holds-barred opinions, insights and reaction (clue is in the title) to the biggest stories of the week. New episodes every Wednesday, wherever you ...

Raptors win their fifth road game of the season.

Here’s a roundup of reaction to Glenn’s press conference: New #Jets HC Aaron Glenn is bringing the energy: “Put your seatbelts on and get ready for the ride…. We’re the freaking New York ...

President Donald Trump's nomination of Robert F. Kennedy Jr. for US Health Secretary has officially been confirmed — a move that every Senate Democrat and lone Republican Mitch McConnell opposed ...

Figure 2. Schematic illustration of the biosynthesis of amaryllidaceae alkaloids. Biosynthetic pathway of galantamine. PAL, phenylalanine ammonia-lyase; C4H, cinnamate 4-hydroxylase; TyDC, tyrosine ...