Repair of liver injury is initiated by interactions between injured hepatocytes and liver sinusoidal endothelial cells (LSEC), however, chronic injury can lead to fibrosis. Here, using a ...

Objective Vascular remodelling during liver damage involves loss of healthy liver sinusoidal endothelial cell (LSEC) phenotype via capillarisation. Hedgehog (Hh) signalling regulates vascular ...

referred to as liver zonation, along which hepatocyte and sinusoidal function varies. The portal triads consist of mesenchymal cells surrounding the portal vein (PV), hepatic artery (HA), and the ...

由多糖荚膜包裹的致病菌（encapsulated bacterium, 荚膜细菌）引起的血流感染是导致人类脓毒症和死亡的一个主要原因。医学界早就认识到重症血流感染通常发生在婴幼儿、老年人和免疫力低下的“弱势群体”，而极少发生在健康青壮年个体。这个流行病学现象暗示青壮年个体中存在识别与清除侵袭性细菌的天然免疫力，但目前对这种 “健康免疫力”的机制缺乏认知。

The liver is a large internal organ that is under your right ribs just beneath your right lung. It has two lobes (sections). The liver is made up mainly of cells called hepatocytes. It also has other ...

These include reduction in portal pressure, improved liver sinusoidal endothelial and hepatic microvascular dysfunction, decreased fibrogenesis, protection against ischaemia/reperfusion injury, safe ...

Massive infiltration of liver sinusoids by lymphoma cells (Figure 1) and NRH (Figures 1 and 2) was confirmed. The patient was therefore diagnosed with primary splenic lymphoma and hepatic ...

What Does Liver Pain Feel Like? Your liver is a football-sized organ that sits under your ribs. It filters and cleans your blood, stockpiles energy, helps you fight infections and diseases ...

Feb. 6, 2025 — The research found that heavy drinkers with either diabetes, high blood pressure or a high waist circumference are as much as 2.4 times more likely to develop advanced liver ...

Cirrhosis is a condition in which scar tissue gradually replaces your healthy liver cells. It usually happens over a long period, often due to hepatitis, alcohol use disorder, or metabolic ...