Isocitrate dehydrogenase (IDH) is an oncogene, and the expression of a mutated IDH promotes cell proliferation and inhibits cell differentiation. IDH exists in three different isoforms, whose mutation ...

The presence of mutant forms of isocitrate dehydrogenase 1 (IDH1) is a key factor in determining the prognosis ... 2007; Meurman and Uittamo, 2008). Therefore, the mechanism underlying the link ...

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The Clean Development Mechanism (CDM), defined in Article 12 of the Protocol, allows a country with an emission-reduction or emission-limitation commitment under the Kyoto Protocol (Annex B Party) to ...

However, clinic investigations revealed that DNA methylation reduction does not correlate with a clinical response, and relapse is prevalent. To gain a better understanding of its anti-tumor mechanism ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

(Photo Credit: E+/Getty Images) The lactate dehydrogenase (LDH) test looks for signs of damage to your body’s tissues. Cars need gas or electricity to go. Your cells need an enzyme (proteins ...

Cells were pretreated with PRMT1 inhibitor MS023 overnight prior to Seahorse analysis. C. Protein levels of lactate dehydrogenase A (LDHA) and p-Y10-LDHA in 6133 and 6133-PRMT1 cells by Western ...

Shaffer, LR ∙ Kaplan, DE ∙ Taddei, TH ∙ et al.

Copyright: © 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Alcohol use disorder is a ...