Recent groundbreaking collaborative efforts have brought the field of Pediatric inflammatory bowel disease (IBD) research to the threshold of a new era in our understanding of the pathogenesis and ...

Crohn's disease and ulcerative colitis are idiopathic, chronic, relapsing, inflammatory conditions that are immunologically mediated. Although their exact etiologies remain uncertain, results from ...

but such associations make it highly likely that many additional genes will be implicated in the pathogenesis of IBD, while others will be associated with extraintestinal disease (e.g. HLA-B27 and ...

More information: Robert D Little et al, Pathogenesis and precision medicine for predicting response in inflammatory bowel disease: advances and future directions, eGastroenterology (2024).

While some medications are available for IBD treatment, disease remission remains suboptimal ... of including such cell types to portray IDB pathophysiology accurately. Using the three cytokines ...