More information: Maryam Kazerani et al, Histone methyltransferase SETDB1 safeguards mouse fetal hematopoiesis by suppressing activation of cryptic enhancers, Proceedings of the National Academy ...

Yushenova further demonstrated that bdelloids possess a histone methyltransferase that preferentially recognizes 4mC marks on DNA, using them to steer its methylation of histones. The two ...

These include DNA methyltransferase and histone deacetylase (HDAC) inhibitors. Further candidates, including inhibitors of acetyl-lysine readers (bromodomain-containing proteins), are undergoing ...