SLC25A1 drives citrate export from the mitochondria to the cytosol, where it fuels acetyl-CoA synthesis by ATP citrate lyase (ACLY). This acetyl-CoA supply sustains FSP1 acetylation and prevents its ...

Examples include DNA methylation and histone acetylation, which can turn genes on or off. Despite their differences, both mechanisms contribute to molecular aging. Researchers have long speculated ...

Laboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Pharmaceutical Sciences, Central University of Punjab, Bathinda 151 401, India ...

Histone post-translational modifications (PTMs) mediate the interplay between metabolism and epigenetics, influencing health and disease. Beyond acetylation, short-chain lysine acylations like ...

Acetylation of these amines with acetyl transferases converts amines to N-acetyl amines (acetamides) and stops the formation of the positive charges. On the other hand, deacetylation of acetamides ...