This in turn contributes to the loss of hepatocyte microvilli and sinusoidal endothelial fenestrae, which result in deterioration of hepatic function. Kupffer cell (macrophage) activation ...

Polyploidy, the existence of cells containing more than one pair of chromosomes, is a well-known feature of mammalian hepatocytes. Polyploid hepatocytes are found either as cells with a single ...

Metabolic requirements of dividing hepatocytes are prerequisite for liver regeneration after injury. In contrast to transcriptional dynamics during liver repair, its metabolic dependencies remain ...

You have full access to this article via your institution. Figure 2: Differential interaction of Apo2L trail versions with hepatocytes.

The discovery that RIPK1 deficiency sensitizes the liver to acute injury and hepatocyte apoptosis is based on convincing evidence, highlighting the importance of RIPK1 in maintaining liver homeostasis ...

Hamilton and McMichael 1 and Matthews 2 have recently suggested mechanisms to explain features of intestinal disaccharide absorption which are dependent on the structure of the microvilli and ...

2007), renal cells (Salahudeen et al., 2000) and hepatocytes (Duret et al., 2015; Aghdaie et al., 2020) and ranging from a few hours (e.g., 4–6 h for hearts and lungs, 12 h for liver) to a few days (e ...