This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

To directly examine the interplay between mutant p53 or Mdm2 and wild type p53 in gene occupancy and expression, an integrated RNA-seq and ChIP-seq analysis was performed in vivo using isogenically ...

To investigate the expression patterns of Nectin-4, the target molecule of the antibody-drug conjugate enfortumab vedotin (EV), in relation to histological and molecular subtypes of urothelial bladder ...

Understanding the reprogramming of gene expression and metabolism is critical for the success of somatic embryogenesis-based plant tissue regeneration. Here, the authors report single-cell RNA ...

But a window has been opened for acknowledging that, as a matter of law, protecting human expression is qualitatively different from enabling algorithmic manipulation of human attention.

Sunlight melts snowflakes. Fire turns logs into soot and smoke. A hot oven will make a magnet lose its pull. Physicists know from countless examples that if you crank the temperature high enough, ...

A new study commissioned by the city mapped the severity of extreme heat and poor air quality around Bloomington to focus mitigation efforts. Bloomington’s Assistant Director of Sustainability ...

A heat mapping project in the Reno-Sparks area has revealed how temperatures vary across the Truckee Meadows. Led by the Nevada State Climate Office at the University of Nevada, Reno, and Desert ...