This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

To directly examine the interplay between mutant p53 or Mdm2 and wild type p53 in gene occupancy and expression, an integrated RNA-seq and ChIP-seq analysis was performed in vivo using isogenically ...

The TP53 gene is a gene that is mutated in many cancers ... the small molecules noted (which inhibit the binding of MDM2 to TP53), phytonutrients in some plant-based foods may directly reduce MDM2 ...

To investigate the expression patterns of Nectin-4, the target molecule of the antibody-drug conjugate enfortumab vedotin (EV), in relation to histological and molecular subtypes of urothelial bladder ...

But a window has been opened for acknowledging that, as a matter of law, protecting human expression is qualitatively different from enabling algorithmic manipulation of human attention.

And if you'd like even more yarn craft inspiration, don't miss our crochet patterns for babies, too. Beginner, intermediate and advanced knitters, grab your needles and yarn and get started on one of ...

Sunlight melts snowflakes. Fire turns logs into soot and smoke. A hot oven will make a magnet lose its pull. Physicists know from countless examples that if you crank the temperature high enough, ...

A new study commissioned by the city mapped the severity of extreme heat and poor air quality around Bloomington to focus mitigation efforts. Bloomington’s Assistant Director of Sustainability ...