This manuscript focuses on the identification of RNA crosslinks within the HIV RNA genome under different conditions i.e. in infected cells and in virions using a new method called HiCapR. These cross ...

Curing HIV will be harder than curing cancer. Apart from a few 'miracle' cases, antiretrovirals only suppress HIV, they don't ...

A) Experimental design of HiCapR for profiling RNA-RNA interactions and dynamics of the HIV genome. Based on the simplified SPLASH protocol, HiCapR incorporates a post-library probe-based ...

Once inside human cells, HIV integrates the viral genome into that of the human host. Ultimately, the virus uses our body's machinery to produce copies of itself and spread infection. The HIV-1 ...

but the virus still remains embedded and hidden in the human genome. Seven people are confirmed to have been cured of HIV with a stem cell therapy used to replace all the immune cells in their bodies.

Analysis Reveals an Additional Mechanism Behind Statin Therapy's Heart-Related Benefits in People With HIV Dec. 11, 2024 — Investigators who previously found that a daily statin pill helps ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

HIV-1, like other viruses ... was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus to produce the correct ...

With 10K genomic data now publicly available, India takes a major leap in genetic research. In today’s 'Knowledge Nugget', ...

HIV drug susceptibility tests can evaluate either the genotype or phenotype of the predominant viral quasispecies. The HIV genotype refers to the actual DNA sequence of the virus; the phenotype ...