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News Medical on MSNGranzyme K identified as key trigger of complement system in autoimmune diseasesOur immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that ...
These cells were found to promote airway inflammation through the characteristic effector molecule Granzyme K (GZMK), which is a serine protease involved in inflammatory pathway activation.
Study uncovers a pathogenic subset of memory T-cells that promote tissue inflammation and highlights a potential target for treating nasal polyps and other inflammatory airway diseases. Study ...
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