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This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...

The ultrasound measurements revealed a sustained decline in tumor vascular index following radiation therapy that correlated with a significant infiltration of CD8 + T cells into tumors.

Tumor-associated macrophages (TAMs) are a phenotypically diverse, highly plastic population of cells in the tumor microenvironment (TME) that have long been known to promote cancer progression. In ...

Many cells comprise the tumor microenvironment, but endothelial cells are particularly crucial. They line blood vessels, regulating blood flow and inflammation, and their cell junctions are the ...

Aggressive brain tumors, specifically glioblastomas, have been found to contain a distinct population of immune cells, myeloid-derived suppressor cells (MDSCs), that support tumor growth.

Activation of mTORC1 is essential for anti-tumor function of iNKT cells. The mechanisms underlying impaired mTORC1 activation in intratumoral iNKT cells remain unclear. Via generating Vam6 +/-mice and ...

This is because the primary tumor continuously releases cancer cells into the blood. These circulating tumor cells (CTCs) can join together into small clusters of up to a dozen cells and settle in ...

While it is true that lymphatic vessels promote metastasis, they are also essential for transporting immune cells and activating the anti-tumor immune response," explains Stéphanie Hugues ...