Coordination of cell cycle with metabolism exists in all cell types that grow by division. It serves to build a new cell, (i) fueling building blocks for the synthesis of proteins, nucleic acids, and ...

Itaconate is a crucial anti-infective and anti-inflammatory immunometabolite that accumulates upon disruption of the Krebs cycle in effector macrophages undergoing ... Mesaconate downregulates ...

A Nobel Prize, of course. Such was the case for Hans Krebs, the biochemist who nabbed the award in 1953 for discovering the citric acid cycle, or “Krebs cycle”—the cellular pathway that converts ...

1Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, China. 2Shandong Engineering Research Center of ...

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New mobile apps from the Chinese artificial intelligence (AI) company DeepSeek have remained among the top three “free” downloads for Apple and Google devices since their debut on Jan.

This switch to glycolysis for ATP synthesis, called the Warburg effect ... Restitution of pyruvate dehydrogenase activity enables the irreversible oxidation of pyruvate to acetyl-CoA, which can then ...

ATP production by the Krebs cycle, and fatty acid metabolism and increased proteins related to nonoxidative metabolism including pyruvate metabolism, gluconeogenesis, and lipid metabolism. 67 These ...