AceLink is advancing a small-molecule treatment option for Fabry disease that could provide a more convenient alternative to ...

Figure 3. Fatty acid elongation by the ELOVL family of enzymes. Diagram of the four-step fatty acid elongation cycle indicating the mammalian (ALL CAPITALS) and the yeast enzymes involved in each step ...

Another portion of this ceramide is transported to the Golgi complex, where it is converted to either glucosylceramide on the cytosolic side of the Golgi via glucosylceramide synthase, or to ...

Spur Therapeutics today announced positive feedback from its end-of-Phase 2 (EOP2) meeting with the U.S. Food and Drug Administration (FDA), supporting its planned Phase 3 trial for FLT201, an ...

Six metabolites (diglyceride (DG, 18:3/24:0), DG (22:0/24:0), phytosphingosine, galabiosylceramide (18:1/24:1), triglyceride (15:0/16:1/o–18:0), and glucosylceramide (18:1/24:0)) were finally selected ...