A nonfunctional mutant of a reporter gene (W in the figure) is introduced or is present in a cell (a). In the recombinant targeting vector (b), the viral genes are replaced by a sequence that is ...

USC has received a $6m grant from the California Institute for Regenerative Medicine (CIRM) to advance a new gene therapy for ...

Conditional gene targeting based on excision or inversion of loxP-flanked DNA segments by Cre recombinase is a powerful technology for the analysis of gene function, but unexpected expression ...

Steps in the production of gene-targeted mice include: Construction of a gene-targeting vector from the isogenic genomic DNA Electroporation of the targeting vector into embryonic stem cells and ...

Researchers are enhancing the best features of AAV capsids and overcoming their limitations to accelerate gene-based therapies.

You will be redirected to our submission process. The recent development of new gene targeting related tools (e.g. base editors, prime editing, GRAND, pfAGO, SHERLOCK, DETECTR, PAC-MAN, ABACAS, etc.) ...

Pluripotent stem cells can be genetically labeled to facilitate differentiation studies. In this paper, we describe a gene-targeting protocol to knock in a GFP cassette into key gene loci in human ...

The California Institute for Regenerative Medicine has awarded a $6 million grant to USC investigators pioneering a new first-of-its-kind genetic therapy for glioblastoma, a severe form of brain ...

The company's lead experimental gene therapy is targeting a treatment for cardiovascular disease. A Montgomery County biopharmaceutical company working on a gene therapy treatment for ...

Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation ...

FOX 4 Dallas-Fort Worth Rep. Gene Wu on Texas targeting China Posted: December 8, 2024 | Last updated: December 8, 2024 Texas Governor Greg Abbott has his eyes on China in the next legislative ...

Researchers find blocking the KCNB2 gene can slow tumor growth, paving the way for next-gen treatments for childhood brain cancer.