Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...

Functional protein design, particularly for proteins ... complex molecular–protein interactions and capturing sequence-structure dependencies. PocketGen addresses these issues, offering a ...

Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each ...

A new study published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions ...

Researchers developed ProtGPS, an AI tool that predicts protein localization in cells and how mutations affect disease. The ...

Evolution has been fine-tuning life at the molecular level for billions of years. Proteins, the fundamental building blocks of life, have evolved through this process to perform various biological ...

The protein was then synthesized and tested in the lab. It glowed—a clear sign of success. The AI had effectively charted a ...

Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill their functions. A study reveals why this assembly often begins during the very process of protein synthesis or ...