"Studies have shown that vulnerability to Alzheimer's-related changes in the brain increase in women from pre- to ...

The degeneration typically begins when a person is in their 20s. It becomes more severe when people are beyond their 70s. People may find that their pain is worse when they wake up in the morning ...

In an autopsy-confirmed cohort, they found that plasma p-Tau217 flagged the presence of amyloid and tau pathology with high accuracy in people with frontotemporal dementia. This matters, because FTD ...

AL001 (Latozinemab), developed by Alector, is an investigational monoclonal antibody designed to treat Frontotemporal Dementia (FTD) caused by the loss of progranulin. It works by targeting and ...

Approximately half of the participants were found to have 1 or more lobar microbleeds, while 8 participants displayed 1 or more lobar ICH. None of the participants were found to have disseminated ...

Alzheimer's pathology in syndromes related to frontotemporal lobar degeneration correlated with worse cognitive performance. A blood test identified clinically relevant Alzheimer's disease ...

Historically, frontotemporal lobar degeneration (FTLD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) were classified on the basis of distinct clinical and pathological ...

Background Amyotrophic lateral sclerosis overlaps aetiologically and genetically with frontotemporal dementia and occurs in both familial and apparently sporadic forms. The most commonly implicated ...

This study has been supported by the German Consortium for Frontotemporal Lobar Degeneration, funded by the German Federal Ministry of Education and Research (BMBF; grant no. FKZ01GI1007A). Based on ...