GlobalData on MSN4mon
Viking reports data from X-linked adrenoleukodystrophy trial
An exploratory objective assessed VK0214's effects on plasma levels of very long-chain fatty acids (VLCFAs), the biomarkers ...
Medscape2mon
Adrenoleukodystrophy: Recent Advances in Treatment and Disease Etiology
HSCT may be a suitable treatment for X-linked ALD adults with early signs of cerebral involvement. Very long-chain fatty acid levels and adrenoleukodystrophy protein (ALDP)-deficiency are strongly ...
Medscape27d
Genetics of Alcoholic and Nonalcoholic Fatty Liver Disease
When considering genetic modifiers of ALD and NAFLD, one should first consider those genes that influence etiologic factors causally linked to the disease. These are exemplified by the associated ...
EurekAlert!2mon
Interorgan crosstalk in the pathogenesis of alcohol-related liver disease (ALD). (IMAGE)
In individuals with ALD, levels of short-chain fatty acids (SCFAs), typically ... The production of bile acids (BAs) is regulated by the farnesoid X receptor (FXR); however, alcohol diminishes ...
Hosted on MSN1mon
Targeting bile acid pathways offers hope for liver disease treatment
fatty liver disease (MASLD), and alcoholic liver disease (ALD). In cholestasis, bile flow becomes obstructed, leading to a buildup of bile acids in the liver. This can cause significant liver injury.