This important study reports single-nucleus multiomics-based profiling of transcriptome and chromatin accessibility of mouse XX and XY primordial germ cells (PGCs). The main conclusions of this study, ...

One method for quantitative evaluation of the state of cells is to track cell metabolism through analysis of the culture medium; however, it’s not possible to gain an accurate understanding of the ...

USC is resistant to cytotoxic chemotherapy and is responsible for most recurrences and deaths from endometrial cancer. USC has a unique gene expression profile. Molecular markers can aid in ...

Cancer markers like CA-125, HE4, and CA-19-9 might be elevated in the blood ... Molecular Pathways and Targeted Therapies for Malignant Ovarian Germ Cell Tumors and Sex Cord-Stromal Tumors: A ...

Similar to OC, endometrial malignancies tend to carry favorable prognoses when early detection is realized. Diagnosis at a later stage, however, typically coincides with a poor prognosis and a ...

NEW YORK, Jan. 16, 2025 /PRNewswire/ -- The Food and Drug Administration (FDA) approved the first mesenchymal stromal cell (MSC) therapy, RYONCIL®, indicated for steroid-refractory acute graft ...

These results suggest their potential as diagnostic markers. Numerous evidence has been suggested that the ceRNA regulatory ... For example, miR-119a is downregulated in the ectopic stromal cells ...

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

Decidualization of endometrial stromal cells is the fundamental requirement for endometrial receptivity and the maintenance of a normal pregnancy, even though endometrial receptivity is made up of a ...