The expression of host miRNAs is affected by virus invasion, which also affects virus replication. Increasing evidence has demonstrated that miRNA influences RNA virus multiplication by binding ...

In 2023, he received the prestigious Sabin Vaccine Institute Gold Medal for developing other innovative vaccines for Ebola Zaire, smallpox, Japanese encephalitis, and West Nile virus, among others.

Laboratory diagnosis of Ebola virus disease (EVD) plays a critical role in outbreak response efforts; however, establishing testing strategies for this high-biosafety-level pathogen in resource-poor ...

A suspected Ebola exposure at a Manhattan urgent-care facility had two patients rushed to the hospital by emergency workers in hazmat suits Sunday – but the disease was ruled out. The patients ...

You’ve certainly heard about antibodies, peptides, and even DNA as therapeutics, but what about RNA? In this review, we take a look at what’s happening ... respectively – use mRNA technology to encode ...

The Marburg virus, which belongs to the Ebola family, is known to be highly lethal, with a mortality rate of 90%. The epidemic has already injured dozens of people and claimed eight lives.

CEPI said the nasal administration could help to achieve mucosal immunity, a key for reducing virus transmission. Spray-drying for RNA-based vaccines could make them more practical ... Two more ...

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is read by ribosomes to generate protein (translation). Biologically active RNAs ...

This assembly process can vary depending on the type of virus-RNA viruses and DNA viruses have distinct mechanisms and locations for assembly. Once assembly, the progeny viruses are released from the ...

an RNA structure normalization tool used in RNA-Puzzles. the RNA 3D structure comparison metrics used in RNA-Puzzles assessment, including RMSD (all-atom), P value, Interaction Network Fidelity and ...

It also comes two days after Uganda's Health Ministry reported six new cases of the virus, as the country struggles to contain the outbreak first declared on January 30. "To further support Uganda's ...